Epstein-Barr Virus, Quantitative PCR, Whole Blood
Ordering Recommendation
Quantify Epstein-Barr virus (EBV) viral load as an aid in monitoring EBV-related disease.
Quantitative Polymerase Chain Reaction
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Lavender (EDTA) or pink (K2EDTA).  
Specimen Preparation
Transport 1 mL whole blood. (Min: 0.5 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Plasma (refer to Epstein-Barr Virus Quantitative PCR, ARUP test code 0051352). Heparinized specimens.  
Specimen source required.  
Ambient: 7 days; Refrigerated: 7 days; Frozen: 7 days.  
Reference Interval
Not detected
Interpretive Data
The quantitative range of this assay is 2.6-7.6 log copies/mL (390-39,000,000 copies/mL)

A negative result (less than 2.6 log copies/mL or less than 390 copies/mL) does not rule out the presence of PCR inhibitors in the patient specimen or EBV DNA nucleic acid in concentrations below the level of detection of the assay. Inhibition may also lead to underestimation of viral quantitation.

No international standard is currently available for calibration of this assay. Caution should be taken when interpreting results generated by different assay methodologies.

Compliance Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.
The limit of quantification for this DNA assay is 2.6 log copies/mL (390 copies/mL). If the assay DID NOT DETECT the virus, the test result will be reported as "<2.6 log copies/mL (<390 copies/mL)." If the assay DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0051339Epstein-Barr Virus, Quant. Source, WB
0051351Epstein-Barr Virus, Quant. Log53774-6
0051821Epstein-Barr Virus, Quant. Interp5005-4
2002318Epstein-Barr Virus, Quant. Copy/mL32585-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • EBV
  • EBV Quant PCR Whole Blood
  • EBV quantitative, whole blood
  • EBV WB, Quant PCR
  • herpes
  • HHV-4
  • Human herpesvirus 4
  • Viral load monitoring