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Epstein-Barr Virus by Quantitative PCR
0051352
Ordering Recommendation

Quantify Epstein-Barr virus (EBV) viral load as an aid in monitoring EBV-related disease.

Mnemonic
EBV QNT
Methodology
Quantitative Polymerase Chain Reaction
Performed
Sun-Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA), Pink (K2EDTA), or Serum Separator Tube (SST). Also acceptable: CSF. 
Specimen Preparation
Separate serum or plasma from cells. Transfer 1 mL serum, plasma, whole blood, or CSF to a sterile container. (Min: 0.5 mL) 
Storage/Transport Temperature
Frozen.
Whole Blood: Refrigerated. 
Unacceptable Conditions
Heparinized specimens. 
Remarks
Specimen source required. 
Stability
Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year
Whole Blood: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 week 
Reference Interval
Not detected
Interpretive Data
The quantitative range of this assay is 2.6-7.6 log copies/mL (390-39,000,000 copies/mL)

A negative result (less than 2.6 log copies/mL or less than 390 copies/mL) does not rule out the presence of PCR inhibitors in the patient specimen, or EBV DNA nucleic acid in concentrations below the level of detection of the assay. Inhibition may also lead to underestimation of viral quantitation.

No international standard is currently available for calibration of this assay. Caution should be taken when interpreting results generated by different assay methodologies.

Compliance Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.

Note
The limit of quantification for this DNA assay is 2.6 log copies/mL (390 copies/mL). If the assay DID NOT DETECT the virus, the test result will be reported as "<2.6 log copies/mL (<390 copies/mL)." If the assay DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."
CPT Code(s)
87799
Components
Component Test Code*Component Chart NameLOINC
0051338EBV by Quantitative PCR, Source31208-2
0051351EBV by Quantitative PCR, Log copy/mL53774-6
0051821EBV by Quantitative PCR, Interp5005-4
2002318EBV by Quantitative PCR, Copy/mL32585-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • EBV
  • EBV Quant PCR
  • EBV Quant PCR Whole Blood
  • EBV quantitative
  • herpes
  • HHV-4
  • Human herpesvirus 4
  • Viral load monitoring