Myelin Associated Glycoprotein (MAG) Antibody, IgM
0051285
Ordering Recommendation
Stand-alone test for autoimmune neuropathies. Test by itself is not diagnostic and should be used in conjunction with other clinical parameters to confirm disease.
Mnemonic
MAGM ELISA
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Tue, Thu, Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
- Patient Preparation
- Collect
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)
- Storage/Transport Temperature
- Refrigerated.
- Unacceptable Conditions
- Urine. Contaminated, heat inactivated, hemolyzed, severely lipemic specimens.
- Remarks
- Stability
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval
Less than 1000 TU
Interpretive Data
An elevated IgM antibody concentration greater than 999 TU against myelin-associated glycoprotein (MAG) suggests active demyelination in peripheral neuropathy. A normal concentration (less than 999 TU) generally rules out an anti-MAG antibody-associated peripheral neuropathy.
TU=Titer Units
TU=Titer Units
Compliance Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Note
CPT Code(s)
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0051285 | MAG Antibody, IgM Elisa | 17314-6 |
Aliases
- MAG Ab
- MAG Antibody
- MAG Antibody by ELISA
- MAG IgM