Human Immunodeficiency Virus 1, vircoTYPE by Sequencing (INACTIVE as of 01/06/14. Refer to 0055670)
Ordering Recommendation
Reverse Transcription Polymerase Chain Reaction/Sequencing/Phenotype Interpretation
3-7 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Lavender (EDTA), pink (K2EDTA) or plasma preparation tube. 
Specimen Preparation
Separate plasma from cells within 6 hours. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Serum. Heparinized specimens. 
Please submit most recent viral load and test date, if available 
On cells: Ambient: 6 hours; After separation from cells: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 4 months 
Reference Interval
By report
Interpretive Data
The vircoTYPE HIV-1 software is used in conjunction with HIV-1 sequencing to calculate drug resistance and susceptibility as an aid in the monitoring and treatment of HIV infection. The protease and codons 1-335 of the reverse transcriptase genes are sequenced at ARUP Laboratories, and the sequence is sent to Janssen Diagnostics ( for analysis using its bioinformatics engine. The vircoTYPE HIV-1 Report should be used in conjunction with clinical presentation and other laboratory markers. Response to therapy depends on multiple factors, including percentage of the resistant virus population, dosing and pharmacokinetics, and patient compliance. Resistance interpretations obtained through different test methods should not be used interchangeably.

HIV sequencing is performed using the Abbott Molecular Viroseq HIV-1 Genotyping system. Some insertions or deletions may be difficult to detect with the instrument software. This test may not detect minor HIV-1 populations less than 20 percent of the total population.

Compliance Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

This test may be unsuccessful if the plasma HIV-1 RNA viral load is less than 1,000 HIV-1 RNA copies per mL of plasma.

For a complete list of drugs currently profiled by this assay, please contact ARUP Client Services.
CPT Code(s)
87900; 87901
Component Test Code*Component Chart NameLOINC
0055648Vircotype Information45182-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.