Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA
0051152
 
Ordering Recommendation
Mnemonic
HERP PAN 2
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimen. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or urine. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens. CSF (refer to Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF, test code 0050379 and Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF, test code 0050359).  
Remarks
 
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
0050292Herpes Simplex Virus Type 1 Glycoprotein G-​Specific Antibody, IgG by CIA
Effective February 18, 2014
0.90 IV or less Negative -​ No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
0.91-​1.09 IV Equivocal -​ Questionable presence of IgG antibody to HSV type 1 glycoprotein G. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater Positive -​ IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection.
0050294Herpes Simplex Virus Type 2 Glycoprotein G-​Specific Antibody, IgG by CIA
Effective February 18, 2014
0.90 IV or less Negative -​ No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.91-​1.09 IV Equivocal -​ Questionable presence of IgG antibody to HSV type 2 glycoprotein G. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater Positive -​ IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.
Interpretive Data
Individuals infected with HSV may not exhibit detectable IgG antibody to glycoprotein G in the early stages of infection, and 5-10% of infections may occur with glycoprotein G deficient virus. Detection of antibody presence in these cases may only be possible using a non-type specific screening test.
Note
CPT Code(s)
86695; 86696
Components
Component Test Code*Component Chart Name
0050292HSV 1 Glycoprotein G Ab, IgG
0050294HSV 2 Glycoprotein G Antibody, IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • HSV
  • HSV glycoprotein G type 1 and 2
  • HSV typing 1 and 2