Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA
0051152
Ordering Recommendation
Submit With Order
Mnemonic
HERP PAN 2
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimen. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or urine. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens. CSF (refer to Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF, test code 0050379 and Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF, test code 0050359).  
Remarks
 
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
0050292Herpes Simplex Virus Type 1 Glycoprotein G-​Specific Antibody, IgG by CIA
Effective February 18, 2014
0.90 IV or less Negative -​ No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
0.91-​1.09 IV Equivocal -​ Questionable presence of IgG antibody to HSV type 1 glycoprotein G. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater Positive -​ IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection.
0050294Herpes Simplex Virus Type 2 Glycoprotein G-​Specific Antibody, IgG by CIA
Effective February 18, 2014
0.90 IV or less Negative -​ No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.91-​1.09 IV Equivocal -​ Questionable presence of IgG antibody to HSV type 2 glycoprotein G. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater Positive -​ IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.
Interpretive Data
Individuals infected with HSV may not exhibit detectable IgG antibody to glycoprotein G in the early stages of infection, and 5-10% of infections may occur with glycoprotein G deficient virus. Detection of antibody presence in these cases may only be possible using a non-type specific screening test.
Note
CPT Code(s)
86695; 86696
Components
Component Test Code*Component Chart Name
0050292HSV 1 Glycoprotein G Ab, IgG
0050294HSV 2 Glycoprotein G Antibody, IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • HSV
  • HSV glycoprotein G type 1 and 2
  • HSV typing 1 and 2