Glomerular Basement Membrane Antibody, IgG by Multiplex Bead Assay
0051000
 
Ordering Recommendation
Mnemonic
GBM-G ELIS
Methodology
Semi-Quantitative Multiplex Bead Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Negative: 19 AU/mL or less
Equivocal: 20-25 AU/mL
Positive: 26 AU/mL or greater
Interpretive Data
The presence of anti-glomerular basement membrane (GBM) antibodies by Multiplex Bead Assay, may aid in the diagnosis of Goodpasture syndrome. False positive results may occur due to reactivity against other chains of type IV collagen. If Multiplex Bead Assay is negative but there is strong suspicion for disease, renal biopsy may be indicated. A renal biopsy may also be essential in suspected Goodpasture disease with renal involvement, allowing diagnostic confirmation and assessment of renal prognosis.
Note
CPT Code(s)
83516
Components
Component Test Code*Component Chart Name
0051000GBM Ab, IgG by Multiplex Bead Assay
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Anti-GBM Antibody
  • Anti-GBM Antibody-IgG
  • Anti-Glomerular Basement Membrane Antibody
  • Antiglomerular Basement Membrane Antibody-IgG
  • Basement Membrane Antibody
  • Basement Membrane, Glomerular Antibody
  • GBM Antibody
  • Glomerular Anti-Basement Membrane