Helicobacter pylori Antibody, IgA
Ordering Recommendation
Do not use to diagnose H. pylori; order H. pylori urea breath test (0020646) or fecal antigen by EIA (0065147).
Submit With Order
Semi-Quantitative Enzyme Immunoassay
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).  
Specimen Preparation
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.1 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.  
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
1.7 EV or less: Negative - No significant level of IgA antibody to H. pylori detected.
1.8-2.2 EV: Equivocal - Repeat testing in 10-14 days may be helpful.
2.3 EV or greater: Positive - IgA antibody to H. pylori detected, suggestive of active infection.
Interpretive Data
Helicobacter pylori IgG and IgA antibody seroconversion occur together after 60 days. Samples that have a high titer of both IgG and IgA antibodies to H. pylori in symptomatic individuals may be considered to represent an active infection. However, a positive H. pylori IgA result can only suggest active infection and should be confirmed by bacterial isolation or other diagnostic testing.

For additional information, refer to Helicobacter pylori topic at arupconsult.com

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s)
Component Test Code*Component Chart Name
0050995Helicobacter pylori Antibody IgA
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Camplyobacter
  • H. Pylori IgA Antibody Serology
  • H. pylori IgA antibody test
  • Ulcer Antibody Test