Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG and IgM with Reflex to Type 1 and 2 Glycoprotein G-Specific Ab, IgG
0050916
Ordering Recommendation
 
Mnemonic
HERPR PAN
Methodology
Semi-Quantitative Chemiluminescent Immunoassay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-2 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Refer to individual components. CSF (refer to Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG & IgM (CSF) with Reflex to Type 1 & 2 Glycoprotein G-Specific Ab, IgG, test code 0050364).Refer to individual components.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
 
 
Test Number Components Reference Interval
 Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG 0.89 IV or less: Negative -​ No significant level of detectable HSV IgG antibody.
0.90-​1.09 IV: Equivocal -​ Questionable presence of IgG antibodies. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater: Positive -​ IgG antibody to HSV detected which may indicate a current or past HSV infection.
 Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA 0.89 IV or less: Negative -​ No significant level of detectable HSV IgM antibody.
0.90-​1.09 IV: Equivocal -​ Questionable presence of IgM antibodies.  Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater: Positive -​ IgM antibody to HSV detected which may indicate a current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection.
0050292Herpes Simplex Virus Type 1 Glycoprotein G-​Specific Antibody, IgG by CIA  
 
Effective February 18, 2014  
0.90 IV or less Negative -​ No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
0.91-​1.09 IV Equivocal -​ Questionable presence of IgG antibody to HSV type 1 glycoprotein G.  Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater Positive -​ IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection.
0050294Herpes Simplex Virus Type 2 Glycoprotein G-​Specific Antibody, IgG by CIA  
 
Effective February 18, 2014  
0.90 IV or less Negative -​ No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.91-​1.09 IV Equivocal -​ Questionable presence of IgG antibody to HSV type 2 glycoprotein G.  Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater Positive -​ IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.
 
Interpretive Data
Refer to individual components for interpretive data.  
Note
If HSV 1 and/or 2 IgG is 1.10 IV or greater, then HSV 1 gG-Specific IgG and HSV 2 gG-Specific IgG will be added. Additional charges apply.
CPT Code(s)
86694 and 86694; if reflexed, add 86695 and 86696
Components
Component Test Code*Component Chart Name
0050286HSV Type 1/2 Combined Ab, IgG
0050641HSV 1 and/or 2 Abs, IgM by ELISA
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • glycoprotein type-specific reactivity
  • Herpes Simplex Antibodies, IgG IgM serology
  • Herpes Simplex serology
  • HSV F antibody
  • HSV 1, 2 IgG IgM
  • HSV 1,2
  • HSV 1,2 and glycoprotein reflex
  • HSV 1,2 glycoprotein
  • HSV glycoprotein G
  • HSV glycoprotein G-based type-specific serology