Extractable Nuclear Antigen Antibodies (SSA & SSB)
Semi-Quantitative Multiplex Bead Assay
Refer to individual components
New York DOH Approval Status
This test is New York DOH approved.
- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
- Storage/Transport Temperature
- Unacceptable Conditions
- Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
SSA (Ro) antibody is seen in 70-75% of Sjögren syndrome cases, 30-40% of systemic lupus erythematosus (SLE) and 5-10% of progressive systemic sclerosis (PSS). SSB (La) antibody is seen in 50-60% of Sjögren syndrome cases and is specific if it is the only ENA antibody present. Fifteen to 25% of patients with systemic lupus erythematosus (SLE) and 5-10% of patients with progressive systemic sclerosis (PSS) also have this antibody.
|Component Test Code*||Component Chart Name|
|0050691||SSA (Ro) (ENA) Antibody, IgG|
|0050692||SSB (La) (ENA) Antibody, IgG|
- Sjögren Syndrome (Extractable Nuclear Antigen Antibodies (SSA & SSB))