Secondary-line test for the evaluation of myasthenia gravis. Recommended if first-line diagnostic tests are negative.
Semi-Quantitative Indirect Fluorescent Antibody
This test is New York DOH approved.
- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
- Storage/Transport Temperature
- Unacceptable Conditions
- Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Screen: < 1:40 No antibody detected.
Titer: < 1:40 No antibody detected.
Titers greater than or equal to 1:80 are suggestive of myasthenia; however, striated muscle antibody can be found in rheumatic fever, myocardial infarction, and a variety of post-cardiotomy states. All positives will be titered to endpoint. If Striated Muscle Ab is >1:40, then a titer will be added. Additional charges apply.
86255; if reflexed, add 86256
|Component Test Code*||Component Chart Name|
|0050747||Striated Muscle Antibody, IgG Screen|
|0050748||Striated Muscle Antibody, IgG Titer|
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at email@example.com.
- Anti-Striated Muscle Antibody