Striated Muscle Antibody, IgG with Reflex to Titer
0050746
Ordering Recommendation
Secondary-line test for the evaluation of myasthenia gravis. Recommended if first-line diagnostic tests are negative.
Mnemonic
STM R
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Performed
Mon-Fri
Reported
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma. Contaminated, hemolyzed, or severely lipemic specimens.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Screen:  < 1:40 No antibody detected.
Titer:    < 1:40 No antibody detected.  
Interpretive Data
 
Note
Titers greater than or equal to 1:80 are suggestive of myasthenia; however, striated muscle antibody can be found in rheumatic fever, myocardial infarction, and a variety of post-cardiotomy states.  All positives will be titered to endpoint. If Striated Muscle Ab is >1:40, then a titer will be added. Additional charges apply.
CPT Code(s)
86255; if reflexed, add 86256
Components
Component Test Code*Component Chart Name
0050747Striated Muscle Antibody, IgG Screen
0050748Striated Muscle Antibody, IgG Titer
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Anti-Skeletal Muscle IgG Antibodies
  • Anti-Striated Antibody
  • Anti-Striated Muscle Antibody
  • Muscle (Skeletal) Antibodies
  • Myoid Antibody
  • Skeletal Muscle Antibodies
  • Striational Antibodies