Striated Muscle Antibody, IgG with Reflex to Titer
0050746
 
Ordering Recommendation
Secondary-line test for the evaluation of myasthenia gravis. Recommended if first-line diagnostic tests are negative.
Mnemonic
STM R
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Performed
Mon-Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma. Contaminated, hemolyzed, or severely lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Screen: < 1:40 No antibody detected.
Titer: < 1:40 No antibody detected.
Interpretive Data
Note
Titers greater than or equal to 1:80 are suggestive of myasthenia; however, striated muscle antibody can be found in rheumatic fever, myocardial infarction, and a variety of post-cardiotomy states. All positives will be titered to endpoint. If Striated Muscle Ab is >1:40, then a titer will be added. Additional charges apply.
CPT Code(s)
86255; if reflexed, add 86256
Components
Component Test Code*Component Chart Name
0050747Striated Muscle Antibody, IgG Screen
0050748Striated Muscle Antibody, IgG Titer
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Anti-Skeletal Muscle IgG Antibodies
  • Anti-Striated Antibody
  • Anti-Striated Muscle Antibody
  • Muscle (Skeletal) Antibodies
  • Myoid Antibody
  • Skeletal Muscle Antibodies
  • Striational Antibodies