- Patient Preparation
- Serum separator tube.
- Specimen Preparation
- Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)
- Storage/Transport Temperature
- Unacceptable Conditions
- Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Titer: < 1:40 No antibodies detected.
Compliance Statement Change
Due to reagent kit manufacturer extended backorder, an alternate kit has been validated and implemented by ARUP.
In the presence of acetylcholine receptor (AChR) antibody, striated muscle antibodies, which bind in a cross-striational pattern to skeletal and heart muscle tissue sections, are associated with late-onset myasthenia gravis (MG). Striated muscle antibodies recognize epitopes on three major muscle proteins, including: titin, ryanodine receptor (RyR) and Kv1.4 (an alpha subunit of voltage-gated potassium channel [VGKC]). Isolated cases of striated muscle antibodies may be seen in patients with certain autoimmune diseases, rheumatic fever, myocardial infarction, and following some cardiotomy procedures.
|Component Test Code*||Component Chart Name||LOINC|
|0050747||Striated Muscle Antibodies, IgG Screen||49692-7|
|0050748||Striated Muscle Antibodies, IgG Titer||29998-2|
- Anti-Skeletal Muscle IgG Antibodies
- Anti-Striated Antibody
- Anti-Striated Muscle Antibody
- Muscle (Skeletal) Antibodies
- Myoid Antibody
- Skeletal Muscle Antibodies
- Striational Antibodies