Reticulin Antibody, IgA with Reflex to Titer
0050698
Ordering Recommendation
Do not use this obsolete test for celiac disease screening. Preferred screening test is Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgA (0097709) for individuals with normal levels of serum IgA.
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Mnemonic
RETIC R
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Performed
Mon-Fri
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma. Contaminated, hemolyzed, or severely lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
Reticulin Antibody, IgA Screen < 1:5 No antibody detected
Reticulin Antibody, IgA Titer < 1:5 No antibody detected
Interpretive Data
Note
IgA class reticulin antibodies are found in dermatitis herpetiformis (25%) and celiac disease (60%), but not in other autoimmune problems. IgG class reticulin antibodies are found in other disease states, especially bullous dermatoses, and sometimes in normal patients. All positives are titered to endpoint. If Reticulin Antibody is 1:5, then a titer will be added. Additional charges apply.
CPT Code(s)
86255; if reflexed add 86256
Components
Component Test Code*Component Chart Name
0050699Reticulin Ab, IgA Screen
0050731Reticulin Antibody, IgA Titer
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Cross References
  • Anti-Reticulin Antibody
  • Antireticulin Antibodies
  • ARA