Mycoplasma pneumoniae Antibodies Seroconversion Panel, IgG & IgM (INACTIVE as of 05/19/14: Refer to 0050399)
Ordering Recommendation
Semi-Quantitative Enzyme Immunoassay
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube (acute) AND serum separator tube (convalescent). 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum (acute) AND 0.5 mL serum (convalescent) to individual ARUP Standard Transport Tubes. (Min: 0.1 mL each) Mark specimens clearly as "acute" or "convalescent" with appropriate draw dates. If acute specimen was previously tested by ARUP, convalescent specimen must be submitted within 30 days if seroconversion comparison testing is desired. 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens. 
Testing will not be performed unless both acute and convalescent specimens are available. 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval

Test Number
Reference Interval
0050397Mycoplasma pneumoniae Antibody, IgG< 0.10 U/L: Negative
0.10-0.32 U/L: Equivocal
> 0.32 U/L: Positive
0050398Mycoplasma pneumoniae Antibody, IgM0.76 U/L or less: Negative - No clinically significant amount of M. pneumoniae IgM antibody detected.
0.77-0.95 U/L: Low Positive - M. pneumoniae-specific IgM presumptively detected.  Collection of a follow-up sample in one to two weeks is recommended to assure reactivity.
0.96 U/L or greater: Positive - Highly significant amount of M. pneumoniae-specific IgM antibody detected.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Interpretive Data

If both Mycoplasma pneumoniae IgG values are above 0.32 U/L, a ratio will be calculated and the significance will be noted on the report.
CPT Code(s)
86738 x4
Component Test Code*Component Chart NameLOINC
0050693M. pneumoniae Antibody, IgM Acute5256-3
0050694M. pneumoniae Antibody, IgM Convalescent5256-3
0050695M. pneumoniae Antibody, IgG Acute5255-5
0050696M. pneumoniae Antibody, IgG Convalescent5255-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • M pneumoniae IgG and IgM seroconversions
  • Mycoplasma G/M Ab Seroconversion