SSB (La) (ENA) Antibody, IgG
0050692
Ordering Recommendation
 
Mnemonic
SSB
Methodology
Semi-Quantitative Multiplex Bead Assay
Performed
Sun-Sat
Reported
1-2 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive  
Interpretive Data
SSB (La) antibody is seen in 50-60% of Sjögren syndrome cases and is specific if it is the only ENA antibody present. Fifteen-25% of patients with systemic lupus erythematosus (SLE) and 5-10% of patients with progressive systemic sclerosis (PSS) also have this antibody.  
Note
 
CPT Code(s)
86235
Components
Component Test Code*Component Chart Name
0050692SSB (La) (ENA) Antibody, IgG
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Aliases
  • anti-SjSyndrome B
  • anti-SSB
  • Anti-SSB (La) (ENA) Antibody
  • Sjogren's Antibody
  • SSB (La)