0050676
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Immunoglobulin G, CSF Index

IGG SYN
Example Reports
Abnormal
Normal

Ordering Recommendation

Aids in the diagnosis and monitoring of patients with multiple sclerosis and other inflammatory disease of the nervous system.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

CSF AND serum separator tube.

Specimen Preparation

Centrifuge and separate CSF to remove cellular material. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL CSF AND 1 mL serum to individual ARUP standard transport tubes. (Min: 0.5 mL CSF AND 0.5 mL serum)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Grossly bloody or hemolyzed specimens, grossly lipemic specimens.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 14 days; Frozen: 6 months (if frozen within 24 hours)

Methodology

Quantitative Immunoturbidimetry

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Test Number
 Components
 Reference Interval
  Albumin, CSF 0-35 mg/dL
  Immunoglobulin G
Age Reference Interval (mg/dL)
0-2 years 242-1108
3-4 years 485-1160
5-9 years 514-1672
10-14 years 581-1652
15-18 years 479-1433
19 years and older 768-1632

  Immunoglobulin G CSF 0.0-6.0 mg/dL
  Albumin, Serum 3500-5200 mg/dL
  Albumin Index 0.0-9.0
  CSF IgG Synthesis Rate Less than or equal to 8.0 mg/d
  CSF IgG/Albumin Ratio 0.09-0.25
  IgG Index 0.28-0.66

Interpretive Data

Access complete set of age- and/or gender-specific reference intervals for this test in the ARUP Laboratory Test Directory (https://ltd.aruplab.com).



To ensure accurate result interpretation, it is recommended that both CSF and serum specimens be collected on the same day. If specimens are not collected within this specified timeframe, it is advised to exercise caution when interpreting the results.

Compliance Category

FDA

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
02/20/2024
X
X
X
05/16/2022
X
N/A

CPT Codes

82784 x2; 82040; 82042

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Components

Component Test Code* Component Chart Name LOINC
0050200 Albumin, CSF 1746-7
0050350 Immunoglobulin G 2465-3
0050670 Immunoglobulin G CSF 2464-6
0050671 Albumin, Serum 1751-7
0050672 Albumin Index 1756-6
0050675 CSF IgG Synthesis Rate 14116-8
0080175 CSF IgG/Albumin Ratio 2470-3
0080180 IgG Index 14117-6
3016987 Immunoglobulin G, CSF Index Interp 48767-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Cerebrospinal fluid index
  • CSF index IgG
  • IgG, CSF Index
  • Immunoglobulin G Synthesis Rate
Immunoglobulin G, CSF Index