Immune Complex Panel
0050667
Ordering Recommendation
 
Mnemonic
C1Q/RAJI
Methodology
Quantitative Flow Cytometry/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Tue
Reported
2-9 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Plain red.  
Specimen Preparation
Let stand for 2 hours, then separate serum from cells within 1 hour. Transfer TWO 1.5 mL aliquots of serum to individual ARUP Standard Transport Tubes and freeze immediately. (Min: 0.5 mL/aliquot)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles.  
Remarks
  
Stability
Refer to individual components.  
Reference Interval
 
 
Available Separately Components Reference Interval
0050301C1q Binding Assay Less than 4 µgE/mL is considered negative for circulating complement binding immune complexes.
0050302Raji Cell Immune Complex Assay By report
 
Interpretive Data
Many autoimmune disorders, chronic infections and malignancies are associated with circulating immune complexes. Quantitation of immune complexes assists in staging immunologic disorders.

See Compliance Statement A: www.aruplab.com/CS
Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.
 
Note
Immune complexes bind to Raji Cells via their complement receptors.  The immunoglobulin portion of the immune complex is then detected by flow cytometry with anti-human IgG-FITC.
CPT Code(s)
86332 x2
Components
Component Test Code*Component Chart Name
0050301C1Q Binding Assay
0050302Raji Cell Immune Complex Assay
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • C1q Immune Commplexes
  • C3d and C1q binding
  • Circulating Immune Complex Panel
  • Detection of C3d Circulating Immune Complexes