Extractable Nuclear Antigen Antibodies (RNP, Smith, SSA, & SSB)
0050652
 
Ordering Recommendation
Mnemonic
ENA ABS4
Methodology
Semi-Quantitative Multiplex Bead Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
Refrigerated..  
Unacceptable Conditions
Plasma or other body fluids. Bacterially contaminated or severely lipemic specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
0050470RNP (U1) (Ribonucleic Protein) (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-​40 AU/mL: Equivocal
41 AU/mL or greater: Positive
0050085Smith (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-​40 AU/mL: Equivocal
41 AU/mL or greater: Positive
0050691SSA (Ro) (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-​40 AU/mL: Equivocal
41 AU/mL or greater: Positive
0050692SSB (La) (ENA) Antibody, IgG 29 AU/mL or less: Negative
30-​40 AU/mL: Equivocal
41 AU/mL or greater: Positive
Interpretive Data
Note
CPT Code(s)
86235 x4
Components
Component Test Code*Component Chart Name
0050085Smith (ENA) Antibody, IgG
0050470Ribonucleic Protein (U1) (ENA) Ab, IgG
0050691SSA (Ro) (ENA) Antibody, IgG
0050692SSB (La) (ENA) Antibody, IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Anti-ENA Anti-Ribonuclear Protein
  • Anti-RNP
  • Anti-Sm IgG
  • Anti-U1 RNP
  • Antibodies to Extractable Nuclear Antigens
  • Ribonucleoprotein Autoantibodies
  • RNP (Anti-RNP)
  • RNP (U1) (Ribonucleic Protein) (ENA) Antibody, IgG
  • Ro Ab
  • Scl 70 Antibodies
  • Smith (ENA) Antibody, IgG
  • Smith Antigen
  • Smith Autoantibodies
  • SmRNP Autoantibodies
  • SSA (Ro) (ENA) Antibody, IgG
    Anti-SSA
  • SSA Ro
  • SSB (La) (ENA) Antibody, IgG
    Anti-SSB
  • SSB LA
  • U1 RNP Ab