Cytomegalovirus Antibodies, IgG and IgM
0050622
Ordering Recommendation
Aids in discriminating between current and past cytomegalovirus infection in immunocompetent individuals.
Submit With Order
Mnemonic
CMV PAN
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.Also acceptable: Serum from umbilical cord blood  
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or urine. Contaminated, hemolyzed, or heat-inactivated specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
0050165Cytomegalovirus Antibody, IgG
0.59 U/mL or less: Not Detected.
0.60-​0.69 U/mL: Indeterminate -​ Repeat testing in 10-​14 days maybe helpful.
0.70 U/mL or greater: Detected.
0050553Cytomegalovirus Antibody, IgM
29.9 AU/mL or less: Not Detected.
30.0-​34.9 AU/mL: Indeterminate -​ Repeat testing in 10-​14 days may be helpful.
35.0 AU/mL or greater: Detected -​ IgM antibody to CMV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection.
Interpretive Data
CMV serology is not useful for the evaluation of active or reactivated infection in immunocompromised patients. Molecular diagnostic tests (i.e., PCR) are preferred in these cases.
Note
This test should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).
CPT Code(s)
86644; 86645
Components
Component Test Code*Component Chart Name
0050165CMV Antibody IgG
0050553CMV Antibody IgM
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • CMV Antibodies
  • CMV IgG & IgM
  • Cytomegalovirus (CMV) Antibodies, IgG and IgM, Serum