Epstein-Barr Virus Antibody Panel II
Ordering Recommendation
Aids in determining past or present Epstein-Barr virus (EBV) infection as well as susceptibility to future EBV infection. May be used in conjunction with EBV nuclear antigen to diagnose primary EBV infectious mononucleosis.
Semi-Quantitative Chemiluminescent Immunoassay
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimen plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Unacceptable Conditions
Tissue or urine. Contaminated, grossly hemolyzed, or heat-inactivated specimens.  
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
0050235Epstein-​Barr Virus Antibody to Viral Capsid Antigen, IgG Effective February 19, 2013

17.9 U/mL or less: Not Detected
18.0-​21.9 U/mL: Indeterminate. Repeat testing in 10-​14 days may be helpful.
22.0 U/mL or greater: Detected
0050240Epstein-​Barr Virus Antibody to Viral Capsid Antigen, IgM Effective February 19, 2013

35.9 U/mL or less: Not Detected
36.0-​43.9 U/mL: Indeterminate. Repeat testing in 10-​14 days may be helpful.
44.0 U/mL or greater: Detected
Interpretive Data
CPT Code(s)
86665 x2
Component Test Code*Component Chart Name
0050235EBV Antibody to Viral Capsid Antigen IgG
0050240EBV Antibody to Viral Capsid Antigen IgM
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • EBV Antibodies
  • EBV Antibody Panel II
  • EBV VCA-IgG Ab
  • EBV VCA-IgM Ab
  • Infectious Mononucleosis Antibody Panel
  • VCA (Viral Capsid Antigen) IgG and IgM