Rubella Antibodies, IgG and IgM
0050552
 
Ordering Recommendation
Mnemonic
RUBE G/M
Methodology
Quantitative Chemiluminescent Immunoassay/Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or urine. Contaminated, heat-inactivated, or hemolyzed specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
0050771Rubella Antibody, IgG
Less than 9 IU/mL: Not Detected.
9-​9.9 IU/mL: Indeterminate -​ Repeat testing in 10-​14 days may be helpful.
10 IU/mL or greater: Detected.
0050551Rubella Antibody, IgM
19.9 AU/mL or less: Not Detected.
20.0 -​ 24.9 AU/mL: Indeterminate -​ Repeat testing in 10-​14 days may be helpful.
25.0 AU/mL or greater: Detected -​ IgM antibody to rubella detected, which may indicate a current or recent infection or immunization.
Interpretive Data
Testing immediately post-exposure is of no value without a later convalescent specimen. While the presence of IgM antibodies suggests current or recent infection, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
Note
CPT Code(s)
86317; 86762
Components
Component Test Code*Component Chart Name
0050551Rubella Antibody IgM
0050771Rubella Antibody IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Rubella Ab, IgG IgM
  • Rubella Antibodies, IgG and IgM
  • rubella panel
  • Rubella serology