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Rubella Antibodies, IgG and IgM
0050552
Ordering Recommendation
Mnemonic
RUBE G/M
Methodology
Quantitative Chemiluminescent Immunoassay/Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or urine. Contaminated, heat-inactivated, or hemolyzed specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number
Components
Reference Interval
0050771Rubella Antibody, IgG
Less than 9 IU/mL:Not Detected.
9-9.9 IU/mL:Indeterminate - Repeat testing in 10-14 days may be helpful.
10 IU/mL or greater:Detected.

0050551Rubella Antibody, IgM
19.9 AU/mL or less:Not Detected.
20.0 - 24.9 AU/mL:Indeterminate - Repeat testing in 10-14 days may be helpful.
25.0 AU/mL or greater:Detected - IgM antibody to rubella detected, which may indicate a current or recent infection or immunization.


Interpretive Data
Testing immediately post-exposure is of no value without a later convalescent specimen. While the presence of IgM antibodies suggests current or recent infection, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.


Note
CPT Code(s)
86762 x2
Components
Component Test Code*Component Chart NameLOINC
0050551Rubella Antibody IgM5335-5
0050771Rubella Antibody IgG8014-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Rubella Ab, IgG IgM
  • Rubella Antibodies, IgG and IgM
  • rubella panel
  • Rubella serology