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Toxoplasma gondii Antibodies, IgG and IgM
0050521
Ordering Recommendation

First-line test for identifying visceral T. gondii infection. CDC suggests equivocal or positive results should be retested using a different assay from another reference laboratory specializing in toxoplasmosis testing (IgG dye test, IgM ELISA, reflex to avidity and/or other tests).

Mnemonic
TOXO PAN
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. Also acceptable: Serum from umbilical cord blood. 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent." 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Plasma or urine. Contaminated, heat-inactivated or grossly hemolyzed specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Test Number
Components
Reference Interval
0050770Toxoplasma gondii Antibody, IgGEffective March 3, 2014
7.1 IU/mL or less:Not Detected.
7.2-8.7 IU/mL:Indeterminate - Repeat testing in 10-14 days may be helpful.
8.8 IU/mL or greater:Detected.

0050557Toxoplasma gondii Antibody, IgM
7.9 AU/mL or less:Not Detected.
8.0-9.9 AU/mL:Indeterminate - Repeat testing in 10-14 days may be helpful.
10.0 AU/mL or greater:Detected - Significant level of Toxoplasma gondii IgM antibody detected and may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.



Interpretive Data
Refer to report.

Note
This test should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).
CPT Code(s)
86777; 86778
Components
Component Test Code*Component Chart NameLOINC
0050557Toxoplasma gondii Ab, IgM5390-0
0050770Toxoplasma gondii Ab, IgG8039-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CMV Antibody IgM
  • HSV 1 and/or 2 Abs, IgM by ELISA’ TORCH IgM panel
  • Rubella Antibody IgM
  • Toxoplasma gondii Ab, IgM