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Hemoglobin S, Evaluation with Reflex to RBC Solubility
0050520
Ordering Recommendation

Determines presence of hemoglobin S.

Mnemonic
SCKL
Methodology
High Performance Liquid Chromatography
Performed
Sun-Sat
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA) or pink (K2EDTA). 
Specimen Preparation
Transport 5 mL whole blood. (Min: 0.2 mL) 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Frozen or room temperature specimens. 
Remarks
 
Stability
Ambient: Unacceptable, Refrigerated: 1 week, Frozen: Unacceptable 
Reference Interval
Negative
Interpretive Data


Note
If HPLC detects a peak which suggests Hgb S, then RBC Solubility will be added for confirmation. Additional charges apply.
CPT Code(s)
83021; if reflexed, add 85660
Components
Component Test Code*Component Chart NameLOINC
0050520Hemoglobin S, Evaluation (Sickle Cell)4621-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Hb S
  • Hgb S
  • Sickle Cell Anemia Screen
  • Sickle Cell Disease