Rapid Plasma Reagin (RPR) with Reflex to Titer
0050471
Ordering Recommendation
CDC recommended screening test for syphilis. May use to confirm reactive treponemal test (eg, EIA, CIA) if using so-called reverse algorithm testing.  Preferred test for monitoring treatment response in established syphilis.
Mnemonic
RPRT
Methodology
Semi-Quantitative Charcoal Agglutination
Performed
Sun-Sat
Reported
Within 24 hours  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.25 mL) Also acceptable: Plasma, if testing is completed within 48 hours of collection.  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
CSF or other body fluids.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
 
 
Test Code Components Reference Interval
 Rapid Plasma Reagin (RPR) RPR (+) = Reactive
RPR (-​) = Nonreactive
 Rapid Plasma Reagin (RPR) Titer < 1:1
Interpretive Data
 
Note
If RPR is reactive, then a titer will be added. Additional charges apply.
CPT Code(s)
86592; if reflexed, add 86593
Components
Component Test Code*Component Chart NameLOINC
0050472Rapid Plasma Reagin (RPR)20507-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • RPR Titer Reflex
  • RPR with Reflex to Titer
  • Treponema pallidum with Reflex to Titer