Ordering Recommendation

Initial screening test for syphilis (traditional algorithm). Confirmatory test for reactive treponemal test (eg, EIA, CIA) (reverse algorithm)  Preferred test for monitoring treatment response in established syphilis. 

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.5 mL) Avoid freezing if possible.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, grossly hemolyzed, grossly lipemic, plasma, CSF, or other body fluids.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Particle Agglutination

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
Components
Reference Interval
  Rapid Plasma Reagin (RPR) Non Reactive

Interpretive Data




Component Interpretation
Rapid Plasma Reagin (RPR) RPR (+) = Reactive
RPR (-) = Nonreactive

Compliance Category

FDA

Note

If RPR is reactive, then a titer will be added. Additional charges apply.

Hotline History

N/A

CPT Codes

86592; if reflexed, add 86593

Components

Component Test Code* Component Chart Name LOINC
0050472 Rapid Plasma Reagin (RPR) 20507-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • RPR Titer Reflex
  • RPR with Reflex to Titer
  • Treponema pallidum with Reflex to Titer
Rapid Plasma Reagin (RPR) with Reflex to Titer