Coxiella burnetii (Q-Fever) Antibody IgG, Phase I & II by IFA (INACTIVE as of 01/04/16: Refer to November 2015 Hot Line for Replacement Test: 2012625, ACTIVE 01/04/16)
Ordering Recommendation
Q-F 1,2
Semi-Quantitative Indirect Fluorescent Antibody
Tue, Fri
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" and "convalescent."  
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, hemolyzed, or severely lipemic specimens.  
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Phase I: < 1:16 No antibody detected.
Phase II: < 1:16 No antibody detected.  
Interpretive Data
Single phase II IgG titers of 1:256 and greater are considered evidence of C. burnetii infection at some time prior to the date of the serum specimen. Phase I antibody titers of 1:16 and greater are consistent with chronic infection or convalescent phase of Q-fever.  
CPT Code(s)
86638 x2
Component Test Code*Component Chart NameLOINC
0050463Q-Fever, Phase I IgG Antibody34716-1
0050464Q-Fever, Phase II IgG Antibody34717-9
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  • Coxiella burnetii
  • Coxiella Titer
  • Q Fever Phases I and II antibody