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Mycoplasma pneumoniae Antibody, IgG
0050397
Ordering Recommendation

Panel that combines M. pneumoniae IgG and IgM antibodies is preferred (0050399).

Mnemonic
MYCO-G
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must  be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent." 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens. 
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
< 0.10 U/L: Negative
0.10-0.32 U/L: Equivocal
> 0.32 U/L: Positive
Interpretive Data
Over 50 percent of healthy adults have a relatively high background of specific M. pneumoniae IgG antibodies in their sera, probably because of past M. pneumoniae infections. Therefore, paired sera obtained with a time interval of 1 to 3 weeks are highly recommended in adults to confirm reinfection by M. pneumoniae, which is demonstrated by a significant change in IgG antibodies. A significant change is indicated if one specimen is above 0.32 U/L and the other is below 0.20 U/L.

Note
CPT Code(s)
86738
Components
Component Test Code*Component Chart NameLOINC
0050397Mycoplasma Pneumoniae Antibody IgG5255-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • M pneumoniae antibody IgG
  • M pneumoniae IgG