Rickettsia typhi (Typhus Fever) Antibody, IgM by IFA
0050383
Ordering Recommendation
 
Mnemonic
TYPHU M
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Performed
Tue, Fri
Reported
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Contaminated, hemolyzed, or severely lipemic, specimens.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
< 1:64  Negative - No significant level of Rickettsia typhi IgM antibody detected.
≥1:64  Positive - Presence of IgM antibody to Rickettsia typhi detected, suggestive of recent infection.  
Interpretive Data
This test is for antibodies to Rickettsia typhi. Any antibody reactivity to Rickettsia typhi antigen should, however, also be considered group-reactive for the Typhus Fever group (Rickettsia prowazekii). Seroconversions or an increase between acute and convalescent IgG and IgM titers of at least fourfold is considered strong evidence of recent infection.

While the presence of IgM antibodies suggests recent infection, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.  
Note
 
CPT Code(s)
86757
Components
Component Test Code*Component Chart NameLOINC
0050383Typhus Fever Antibody, IgM5325-6
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Aliases
  • R typhi IgM antibody
  • Typhus Fever Group IgM Antibody