Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG & IgM (CSF) with Reflex to Type 1 & 2 Glycoprotein G-Specific Ab, IgG
0050364
 
Ordering Recommendation
Mnemonic
HERPRCSF
Methodology
Semi-Quantitative Chemiluminescent Immunoassay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory.
Specimen Required
Patient Preparation
 
Collect
CSF.  
Specimen Preparation
Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Specimen types other than CSF. Contaminated or heat-inactivated specimens.  
Remarks
 
Stability
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM, CSF by ELISA 0.89 IV or less; Negative -​ No significant level of detectable HSV IgM antibody.
0.90-​1.09 IV; Equivocal -​ Questionable presence of IgM antibodies. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater; Positive -​ IgM antibody to HSV detected which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection.
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG, CSF 0.89 IV or less: Negative -​ No significant level of detectable HSV IgG antibody.
0.90-​1.09 IV: Equivocal -​ Questionable presence of IgG antibodies. Repeat testing in 10-​14 days may be helpful.
1.10 IV or greater: Positive -​ IgG antibody to HSV detected which may indicate a current or past HSV infection.
0050379Herpes Simplex Virus Type 1 Glycoprotein G-​Specific Antibody, IgG by ELISA, CSF 0.89 IV or less: Negative -​ No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
0.90-​1.10 IV: Equivocal -​ Questionable presence of IgG antibody to HSV type 1. Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past infection.
0050359Herpes Simplex Virus Type 2 Glycoprotein G-​Specific Antibody, IgG by ELISA, CSF 0.89 IV or less: Negative -​ No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.90-​1.10 IV: Equivocal -​ Questionable presence of IgG antibody to HSV type 2. Repeat testing in 10-​14 days may be helpful.
1.11 IV or greater: Positive -​ IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.
Interpretive Data


See Compliance Statement E: www.aruplab.com/CS
Note
If HSV 1/2 IgG, CSF is greater than or equal to 1.10 IV , then HSV 1 gG-Specific IgG, CSF and HSV 2 gG-Specific IgG, CSF will be added. Additional charges apply.
CPT Code(s)
86694 and 86694; if reflexed, add 86695 and 86696
Components
Component Test Code*Component Chart Name
0050394HSV 1/2 Antibody Screen IgG, CSF
0050408HSV 1 and/or 2 Antibodies IgM, CSF
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • glycoprotein type-specific reactivity
  • Herpes Simplex Antibodies, IgG IgM CSF
  • Herpes Simplex CSF
  • HSV 1, 2 IgG IgM CSF
  • HSV 1,2
  • HSV 1,2 and glycoprotein reflex
  • HSV 1,2 glycoprotein CSF
  • HSV CSF antibody
  • HSV glycoprotein G CSF
  • HSV glycoprotein G-based type-specific CSF