Raji Cell Immune Complex Assay
Ordering Recommendation

Detect circulating immune complexes. Consider ordering the panel test, which contains both Raji cell immune complex and C1q binding assays (0050667).

Quantitative Flow Cytometry
2-9 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Plain red or serum separator tube (SST).  
Specimen Preparation
Allow complete clotting of red blood cells (up to 1 hour), then separate serum from cells within 30 minutes and freeze immediately. Transport 1 mL serum. (Min: 0.5 mL) If ordered in conjunction with a C1q Binding Assay, transfer TWO (2) 1 mL aliquots of serum to individual ARUP Standard Transport Tubes.  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles.  
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 30 days  
Reference Interval
By report
Interpretive Data
Many autoimmune disorders, chronic infections and malignancies are associated with circulating immune complexes. Quantitation of immune complexes assists in staging immunologic disorders.

Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.
Immune complexes bind to Raji Cells via their complement receptors. The immunoglobulin portion of the immune complex is then detected by flow cytometry with anti-human IgG-FITC.
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0050302Raji Cell Immune Complex Assay10864-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Immune Complex Assay