Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by CIA
Ordering Recommendation

Not a stand-alone test. Order in conjunction with Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by CIA (0050292).

Semi-Quantitative Chemiluminescent Immunoassay
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum Separator Tube (SST). 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens. 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Effective February 18, 2014
0.90 IV or lessNegative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.91-1.09 IVEquivocal - Questionable presence of IgG antibody to HSV type 2 glycoprotein G.  Repeat testing in 10-14 days may be helpful.
1.10 IV or greaterPositive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.

Interpretive Data
Individuals infected with HSV may not exhibit detectable IgG antibody to type-specific HSV antigens 1 and 2 in the early stages of infection. Detection of antibody presence in these cases may only be possible using a non-type specific screening test.

For CSF specimens refer to Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF (ARUP test code 0050359).
Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0050294HSV 2 Glycoprotein G Antibody, IgG42338-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Herpes Simplex glycoprotein G
  • HerpeSelect
  • HSV 2 typing
  • HSV Type 2 IgG Specific Ab
  • HSV typing
  • HSV-2