Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG
Ordering Recommendation

Not recommended as a stand-alone test. Refer to Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG with Reflex to Type 1 and 2 Glycoprotein G-Specific Ab, IgG (0051708).

Semi-Quantitative Chemiluminescent Immunoassay
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum separator tube. Also acceptable: Serum from umbilical cord blood. 
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transport 1 mL serum. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent." 
Storage/Transport Temperature
Unacceptable Conditions
Urine. CSF (refer to Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG, CSF, ARUP test code 0050394). Contaminated, heat-inactivated, or hemolyzed specimens. 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
0.89 IV or less:Not Detected.
0.90-1.09 IV:Indeterminate - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater:Detected.

Interpretive Data
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Component Test Code*Component Chart NameLOINC
0050286HSV Type 1/2 Combined Ab, IgG27948-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Herpes Simplex Antibodies, IgG
  • Herpes Simplex Serology, Serum HSV 1,2
  • HSV 1 and 2
  • HSV 1, 2 IgG
  • HSV 1,2