Epstein-Barr Virus Antibody to Nuclear Antigen, IgG
0050245
Ordering Recommendation
Order to document past Epstein-Barr virus (EBV) exposure or, in conjunction with other serologic tests, diagnose primary EBV infectious mononucleosis.
Mnemonic
EBV NA
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Mon-Sun
Reported
1-2 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimen plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma. Tissue or urine. Contaminated, grossly hemolyzed, or heat-inactivated specimens.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Effective February 19, 2013

17.9 U/mL or less: Not Detected
18.0-21.9 U/mL: Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected  
Interpretive Data
Interpretive information regarding serologic features of EBV-associated diseases is available at www.arupconsult.com/ebvdx.  
Note
EBNA values obtained with different manufacturers' assay methods may not be used interchangeably.  The magnitude of the reported EBNA level cannot be correlated to an endpoint titer.
CPT Code(s)
86664
Components
Component Test Code*Component Chart Name
0050245EBV Antibody to Nuclear Antigen IgG
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • EBNA Antibody
  • EBNA-IgG Ab
  • EBV Antibodies
  • EBV Antibody to Nuclear Antigen
  • EBV Nuclear Antibody