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Cryofibrinogen
0050190
Ordering Recommendation

Aids in evaluation of patients with vasculitis, macroglobulinemia, or multiple myeloma in whom symptoms occur with exposure to cold.

Mnemonic
CRYO FIB
Methodology
Qualitative Cold Precipitation
Performed
Sun-Sat
Reported
3-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Fasting specimen required. 
Collect
Whole blood drawn in a pre-warmed (37°C) syringe. Specimen may be drawn directly into a pre-warmed lt. blue (sodium citrate) or black (sodium citrate). 
Specimen Preparation
Maintain whole blood at 37°C from collection to transport; do not refrigerate or freeze at any time. Immediately after blood has been obtained, transfer specimen to a pre-warmed blue (sodium citrate) or black (sodium citrate) (if not used for collection). Separate plasma from cells using a 37°C centrifuge, if possible. Transfer 3 mL plasma to an ARUP Standard Transport Tube. (Min: 1 mL) 
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated. 
Unacceptable Conditions
Serum. Heparinized plasma. Grossly hemolyzed or lipemic specimens. 
Remarks
Proper collection and transport of specimen is critical to the outcome of the assay. Quantities less than 3 mL may affect the sensitivity of the assay. 
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable 
Reference Interval
Negative at 72 hours.
Interpretive Data


Note
CPT Code(s)
82585
Components
Component Test Code*Component Chart NameLOINC
0050190Cryofibrinogen29744-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • cryofibrinogen protein
  • Cryofibrinogen, Qualitative, Plasma
  • cryopreciptate
  • Cryoprotein
  • plasma cryofibrinogen