Cryoglobulin, Qualitative
0050185
 
Ordering Recommendation
Mnemonic
CRYGB
Methodology
Qualitative Cold Precipitation
Performed
Sun-Sat
Reported
3-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Fasting specimen preferred.  
Collect
Plain red tube.  
Specimen Preparation
1) Draw approximately 7 mL of blood into a pre-warmed (37°C) plain red tube. Alternatively: draw into a pre-warmed (37°C) syringe and immediately transfer blood to a pre-warmed (37°C) plain red tube. 2) Maintain collected blood at 37°C until clotting is complete. 3) Separate serum from cells within 1 hour of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL) See Remarks.  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated.  
Unacceptable Conditions
Plasma. Serum separator tubes (SST or clot-activating tubes). Grossly hemolyzed or lipemic specimens.  
Remarks
Proper collection and transport of specimen is critical to the outcome of the test. Submitting quantities less than 3 mL may affect the sensitivity of the test.  
Stability
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable  
Reference Interval
Negative at 72 hours.
Interpretive Data
Note
The specimen is examined daily for the presence or absence of cryoglobulins over a period of three days. Cryoglobulins are usually associated with certain plasma cell and lymphoproliferative disorders, but have also been demonstrated in collagen vascular diseases, hepatitis C infection and infections such as infectious mononucleosis and cytomegalovirus disease. They may also be found in low levels in apparently healthy individuals.
CPT Code(s)
82595
Components
Component Test Code*Component Chart Name
0050185Cryoglobulin, Qualitative
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References