Coccidioides immitis Antibodies by Immunodiffusion
0050183
Ordering Recommendation
 
Mnemonic
COCCI-PPT
Methodology
Qualitative Immunodiffusion
Performed
Sun-Fri
Reported
2-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube OR CSF.  
Specimen Preparation
Transfer 0.5 mL serum OR CSF to an ARUP Standard Transport Tube (Min: 0.15 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Bloody or grossly hemolyzed specimens.  
Remarks
  
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
None detected.  
Interpretive Data
Coccidioides infection is demonstrated by the detection of IgM antibody to the Immunodiffusion Tube Precipitin (IDTP) antigen. IgM antibody may be detected 1 to 3 weeks after the onset of primary infection and may suggest active or recent infection. IgM antibody is rarely detected 6 months after infection but may reappear with relapse and may persist in disseminated cases.

IgG antibody may also be demonstrated in response to the Immunodiffusion Complement Fixation (IDCF) antigen and may represent active or past infection. Negative fungal serology does not rule out current infection.  
Note
This test uses culture filtrates of Coccidioides immitis and includes IDCF and IDTP antigens.
CPT Code(s)
86635
Components
Component Test Code*Component Chart NameLOINC
0050183Coccidioides immitis Abs, Precipitin31153-0
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Aliases
  • Coccidioides Antibody (TP Antigen)
  • Coccidioides Antibody (TP Antigen), Immunodiffusion
  • Coccidioides antibody, S
  • Coccidioides Precipitin
  • Coccidioidomycosis IgG/IgM
  • San Joaquin Fever Antibody
  • San Joaquin Valley fever
  • Valley Fever antibodies, Cocci ID