- Patient Preparation
- Serum separator tube or plain red.
- Specimen Preparation
- Keep in warm water (37°C) until processed for transport by laboratory; refrigeration of specimen before separation of serum from cells will adversely affect test results. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.25 mL)
- Storage/Transport Temperature
- Unacceptable Conditions
- Plasma or CSF. Refrigerated whole blood. Contaminated, severely hemolyzed, or lipemic, specimens.
- After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Primary atypical pneumonia can be caused by Mycoplasma pneumoniae, influenza A, influenza B, parainfluenza, and adenoviruses. However, a fourfold rise in the cold agglutinins usually begins to appear late in the first week or during the second week of the disease and begins to decrease between the fourth and sixth weeks. Low titers of cold agglutinins have been demonstrated in malaria, peripheral vascular disease, and common respiratory disease.
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