Varicella-Zoster Virus Antibody, IgG
Ordering Recommendation

Provide evidence of vaccination or past infection with varicella-zoster virus.

Semi-Quantitative Chemiluminescent Immunoassay
Sun - Sat
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum Separator Tube (SST). 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens. 
Label specimens plainly as acute or convalescent. 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (Avoid repeated freeze/thaw cycles) 
Reference Interval
Effective August 20, 2012

134 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody.
135-165 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
166 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection.
Interpretive Data
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

For CSF specimens, refer to Varicella-Zoster Virus Antibody, IgG, CSF (ARUP test code 0054444).
Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0050167Varicella-Zoster Virus Ab, IgG5403-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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