Varicella-Zoster Virus Antibodies, IgG and IgM
0050162
Ordering Recommendation
 
Mnemonic
VZV PAN
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
See individual components.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
 
 
Test Number Components Reference Interval
0050167Varicella-​Zoster Virus Antibody, IgG Effective August 20, 2012

134 IV or less: Negative -​ No significant level of detectable varicella-​zoster IgG antibody.
135-​165 IV: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
166 IV or greater: Positive -​ IgG antibody to varicella-​zoster detected, which may indicate a current or past varicella-​zoster infection.
0099314Varicella-​Zoster Virus Antibody, IgM 0.90 ISR or less: Negative -​ No significant level of detectable varicella-​zoster virus IgM antibody.
0.91-​1.09 ISR: Equivocal -​ Repeat testing in 10-​14 days may be helpful.
1.10 ISR or greater: Positive -​ Significant level of detectable varicella-​zoster virus IgM antibody. Indicative of current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection or immunization.
Interpretive Data
 
Note
 
CPT Code(s)
86787 x2
Components
Component Test Code*Component Chart NameLOINC
0050167Varicella-Zoster Virus Ab, IgG5403-1
0099314Varicella-Zoster Virus Antibody, IgM5404-9
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Aliases
  • Herpes Zoster
  • Varicella Zoster Virus
  • VZV
  • VZV Antibodies, IgG & IgM
  • VZV antibody panel
  • VZV panel