Feedback
Varicella-Zoster Virus Antibodies, IgG and IgM
0050162
Ordering Recommendation

May aid in diagnosing acute infections and detecting past exposure and/or vaccination.

Mnemonic
VZV PAN
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
See individual components.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number
Components
Reference Interval
0050167Varicella-Zoster Virus Antibody, IgGEffective August 20, 2012

134 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody.
135-165 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
166 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection.
0099314Varicella-Zoster Virus Antibody, IgM0.90 ISR or less: Negative - No significant level of detectable varicella-zoster virus IgM antibody.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of detectable varicella-zoster virus IgM antibody. Indicative of current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

Interpretive Data


Note
CPT Code(s)
86787 x2
Components
Component Test Code*Component Chart NameLOINC
0050167Varicella-Zoster Virus Ab, IgG5403-1
0099314Varicella-Zoster Virus Antibody, IgM5404-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Herpes Zoster
  • Varicella Zoster Virus
  • VZV
  • VZV Antibodies, IgG & IgM
  • VZV antibody panel
  • VZV panel