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Complement Components 3 and 4
0050149
Ordering Recommendation

Monitor rheumatologic disease.

Mnemonic
C3C4
Methodology
Quantitative Immunoturbidimetry
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Allow specimen to clot at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.6 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Specimens left to clot at refrigerated temperature. Specimens exposed to repeated freeze/thaw cycles.  
Remarks
 
Stability
Ambient: 8 hours; Refrigerated: 24 hours; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number
Components
Reference Interval
0050150Complement Component 3
0-30 days: 59-121 mg/dL
1 month: 55-129 mg/dL
2 months: 61-155 mg/dL
3 months: 67-136 mg/dL
4 months: 65-182 mg/dL
5 months: 67-174 mg/dL
6 months: 77-179 mg/dL
7-8 months: 78-173 mg/dL
9-11 months: 76-187 mg/dL
1 year: 87-181 mg/dL
2 years: 84-177 mg/dL
3-4 years: 80-178 mg/dL
5-11 years: 80-160 mg/dL
12-17 years: 82-163 mg/dL
18 years and older: 88-201 mg/dL

0050155Complement Component 4
0-30 days: 8-30 mg/dL
1 month: 9-33 mg/dL
2 months: 9-37 mg/dL
3 months: 10-35 mg/dL
4 months: 10-49 mg/dL
5 months: 9-48 mg/dL
6 months: 12-55 mg/dL
7-8 months: 13-48 mg/dL
9-11 months: 16-51 mg/dL
1 year: 16-52 mg/dL
2-4 years: 12-47 mg/dL
5-11 years: 13-44 mg/dL
12-17 years: 14-41 mg/dL
18 years and older: 10-40 mg/dL


Interpretive Data


Note
CPT Code(s)
86160 x2
Components
Component Test Code*Component Chart NameLOINC
0050150Complement Component 34485-9
0050155Complement Component 44498-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • C3 & C4
  • C3/C4