Complement Components 3 and 4
0050149
 
Ordering Recommendation
Monitor rheumatologic disease.
Mnemonic
C3C4
Methodology
Quantitative Immunoturbidimetry
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Allow specimen to clot at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.6 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Specimens left to clot at refrigerated temperature. Specimens exposed to repeated freeze/thaw cycles.  
Remarks
 
Stability
Ambient: 8 hours; Refrigerated: 24 hours; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)  
Reference Interval
Test Number Components Reference Interval
0050150Complement Component 3
0-​30 days: 59-​121 mg/dL
1 month: 55-​129 mg/dL
2 months: 61-​155 mg/dL
3 months: 67-​136 mg/dL
4 months: 65-​182 mg/dL
5 months: 67-​174 mg/dL
6 months: 77-​179 mg/dL
7-​8 months: 78-​173 mg/dL
9-​11 months: 76-​187 mg/dL
1 year: 87-​181 mg/dL
2 years: 84-​177 mg/dL
3-​4 years: 80-​178 mg/dL
5-​11 years: 80-​160 mg/dL
12-​17 years: 82-​163 mg/dL
18 years and older: 88-​201 mg/dL
0050155Complement Component 4
0-​30 days: 8-​30 mg/dL
1 month: 9-​33 mg/dL
2 months: 9-​37 mg/dL
3 months: 10-​35 mg/dL
4 months: 10-​49 mg/dL
5 months: 9-​48 mg/dL
6 months: 12-​55 mg/dL
7-​8 months: 13-​48 mg/dL
9-​11 months: 16-​51 mg/dL
1 year: 16-​52 mg/dL
2-​4 years: 12-​47 mg/dL
5-​11 years: 13-​44 mg/dL
12-​17 years: 14-​41 mg/dL
18 years and older: 10-​40 mg/dL
Interpretive Data
Note
CPT Code(s)
86160 x2
Components
Component Test Code*Component Chart Name
0050150Complement Component 3
0050155Complement Component 4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • C3 & C4
  • C3/C4