Entamoeba histolytica (amebiasis), Antibody, IgG
Ordering Recommendation
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Tue, Fri
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.  
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.  
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
0.79 IV or less: Negative - No significant level of detectable E. histolytica IgG antibody.
0.80-1.19 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.20 IV or greater: Positive - IgG antibody to E. histolytica detected, suggestive of a current or past infection.  
Interpretive Data
Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.  
In the case of extraintestinal complications, a positive antibody can indicate amebiasis even though stool findings are negative.
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0050070E. histolytica (amebiasis), Ab, IgG9522-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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