Estrogen/Progesterone Receptor with Interpretation by Immunohistochemistry
0049210
Ordering Recommendation
 
Mnemonic
ERPR IP
Methodology
Immunohistochemistry
Performed
Mon-Fri
Reported
Within 4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Immunohistochemistry Stain Form Recommended  (ARUP form #32978)Immunohistochemistry Stain Form Recommended (ARUP form #32978)

Specimen Required
Patient Preparation
  
Collect
Tumor tissue.  
Specimen Preparation
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue no later than 1 hour after removal from patient. Fixative duration: 6-72 hours. If sending precut slides, do not oven bake. Transport tissue block or 5 unstained (3-5 micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800)522-2787.(Min: 4 slides).If sending precut slides, do not oven bake.  
Storage/Transport Temperature
Room temperature or refrigerated. Ship in cooled container during summer months.  
Unacceptable Conditions
Paraffin block with no tumor tissue remaining. Specimens with fixation delayed for more than one hour. Specimens fixed in any fixative other than 10 percent neutral buffered formalin. Biopsies fixed for less than 6 hours and greater than 72 hours. Cytology specimens fixed in alcohol.  
Remarks
Document time from tissue acquisition to fixation and fixation duration on submitting requisition or enter at time of order. Include surgical pathology report.  
Stability
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data
Refer to report.

See Compliance Statement A: www.aruplab.com/CS
Statement A: Analyte specific reagents (ASR) are used in many laboratory tests necessary for standard medical care and generally do not require U.S. Food and Drug Administration (FDA) approval or clearance. This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. This test should not be regarded as investigational or for research use.
 
Note
 
CPT Code(s)
88360 x2
Components
Component Test Code*Component Chart Name
0049200Estrogen Receptor IP
0049201% of Nuclei Staining (ER)
0049205Progesterone Receptor IP
0049206% of Nuclei Staining (PR)
0049217Estrog/Progest Receptor Interpretation
2003377Estrogen Receptor Intensity
2003378Progesterone Receptor Intensity
2010754Internal Control Staining
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ER and PR IHC
  • ER, PGR IHC
  • ER, PGR staining
  • ER/PgR
  • ERA & PRA
  • ERPR
  • Steroid Receptor Assay