Chorionic Villus, FISH
Ordering Recommendation
Rapid detection of aneuploidy involving chromosomes X, Y, 13, 18, and 21. Assay  offered in conjunction with chromosome study.
Fluorescence in situ Hybridization
1-3 days  
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Cytogenetic Test Request Form Recommended (ARUP form #43097)Cytogenetic Test Request Form Recommended (ARUP form #43097)

Specimen Required
Patient Preparation
Thaw media prior to collection. Chorionic villus in a sterile, screw-top container filled with tissue culture transport medium (ARUP Supply #32788). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  
Specimen Preparation
DO NOT FREEZE. Do not place in formalin. Transport chorionic villus (CVS) specimen in a sterile, screw-top container filled with tissue culture transport medium.  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Frozen specimens. Specimens preserved in formalin.  
This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Submit the Patient History for Cytogenetic (Chromosome) Studies with the electronic packing list (available at  
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
Interpretive Data

Counseling and informed consent are recommended for genetic testing. Consent forms are available online at

See Compliance Statement C:  
After specimen receipt, results are generally available in an average of 4 days.

This test must be ordered using a Cytogenetic test request form 43097 or through your ARUP interface.  Please submit the Patient History Form - Chromosome Studies with the Electronic Packing List.  The form is available on ARUP's Web site,
CPT Code(s)
88271 x5; 88275 x5; 88291
Component Test Code*Component Chart Name
0040204Chorionic Villus, FISH
2002193EER Chorionic Villus, FISH
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Common trisomy FISH panel
  • CVS
  • Insight
  • prenatal FISH