Chorionic Villus, FISH
0040203
Ordering Recommendation
Rapid detection of aneuploidy involving chromosomes X, Y, 13, 18, and 21. Assay  offered in conjunction with chromosome study.
Mnemonic
FISHCVS
Methodology
Fluorescence in situ Hybridization
Performed
Sun-Sat
Reported
1-3 days  
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Cytogenetic Test Request Form Recommended (ARUP form #43097)Cytogenetic Test Request Form Recommended (ARUP form #43097)

Specimen Required
Patient Preparation
  
Collect
Thaw media prior to collection. Chorionic villus in a sterile, screw-top container filled with tissue culture transport medium (ARUP Supply #32788). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.  
Specimen Preparation
DO NOT FREEZE. Do not place in formalin. Transport chorionic villus (CVS) specimen in a sterile, screw-top container filled with tissue culture transport medium.  
Storage/Transport Temperature
Room temperature.  
Unacceptable Conditions
Frozen specimens. Specimens preserved in formalin.  
Remarks
This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Submit the Patient History for Cytogenetic (Chromosome) Studies with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).  
Stability
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable  
Reference Interval
   
Interpretive Data






See Compliance Statement C: www.aruplab.com/CS
Statement C: The performance characteristics of this test were validated by ARUP Laboratories. The U.S. Food and Drug Administration (FDA) has not approved or cleared this test; however, FDA approval or clearance is currently not required for clinical use of this test. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions. ARUP is authorized under Clinical Laboratory Improvement Amendments (CLIA) and by all states to perform high-complexity testing.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
 
Note
After specimen receipt, results are generally available in an average of 4 days.

This test must be ordered using a Cytogenetic test request form 43097 or through your ARUP interface.  Please submit the Patient History Form - Chromosome Studies with the Electronic Packing List.  The form is available on ARUP's Web site, http://www.aruplab.com/patienthistory
CPT Code(s)
88271 x5; 88275 x5; 88291
Components
Component Test Code*Component Chart NameLOINC
0040204Chorionic Villus, FISH 
2002193EER Chorionic Villus, FISH 
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Common trisomy FISH panel
  • CVS
  • CVS FISH
  • Insight
  • prenatal FISH