B-Type Natriuretic Peptide
0030191
Ordering Recommendation
Aids in diagnosis, prognosis, and management of acute and chronic heart failure.
Mnemonic
BNP
Methodology
Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Time SensitiveTime Sensitive

Specimen Required
Patient Preparation
  
Collect
Lavender (EDTA) or pink (K2EDTA).  
Specimen Preparation
Separate plasma from cells within 2 hours of collection. Transfer 2 mL plasma to an ARUP Standard Transport Tube and freeze within 4 hours of collection. (Min: 0.5 mL)  
Storage/Transport Temperature
Frozen.  
Unacceptable Conditions
Frozen whole blood. Specimens collected in non-EDTA tubes. Specimens frozen in separator tube.  Specimen exposed to repeated freeze/thaw cycles. Refrigerated or room temperature specimens more than 4 hours old. Hemolyzed specimens.  
Remarks
  
Stability
After separation from cells: Ambient: 4 hours; Refrigerated: 4 hours; Frozen: 4 months  
Reference Interval
Refer to Interpretive Data.  
Interpretive Data
A cutoff of 100 pg/mL has been demonstrated to provide the maximal combination of sensitivity, specificity, and negative predictive value for contributing to the diagnosis of congestive heart failure (CHF). A BNP value greater than 100 pg/mL is consistent with a diagnosis of CHF in the appropriate clinical setting. False-positive results are more common in females greater than 75 years of age. Blood concentrations of natriuretic peptides may also be elevated in patients with myocardial infarction and in patients who are candidates for or are undergoing renal dialysis.  
Note
 
CPT Code(s)
83880
Components
Component Test Code*Component Chart Name
0030191B-Type Natriuretic Peptide
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Aliases
  • BNP
  • BNP (Brain Natriuretic Peptide)
  • Brain Natriuretic Peptide
  • Brain Type Natriuretic Peptide
  • Natriuretic Peptide