Protein C and S Panel, Functional
0030182
Ordering Recommendation
Acceptable panel to detect protein C and S deficiencies. Preferred test for detecting protein S deficiency is Protein S Free, Antigen (0098894). Do not order if the individual has been on warfarin therapy in the previous 2-4 weeks.
Submit With Order
Mnemonic
C/S PANEL
Methodology
Clotting
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Serum. Non-frozen or hemolyzed specimens.  
Remarks
Include list of medications.  
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months  
Reference Interval
80-203%
Test Number Components Reference Interval
0030113Protein C, Functional 1-​4 days: 17-​53%
5-​29 days: 20-​64%
30-​89 days: 21-​65%
90-​179 days: 28-​80%
180-​364 days: 37-​81%
1-​6 years: 40-​92%
7-​9 years: 56-​144%
10-​11 years: 59-​143%
12-​13 years: 57-​142%
14-​15 years: 56-​162%
16-​17 years: 68-​154%
18 years and older: 77-​173%
0030114Protein S, Functional Male
1-​89 days: 15-​55%
90-​179 days: 35-​92%
180-​364 days: 45-​115%
1-​5 years: 62-​120%
6 years: 62-​130%
7-​9 years: 66-​140%
10-​11 years: 65-​139%
12-​13 years: 72-​139%
14-​15 years: 68-​145%
16-​17 years: 77-​167%
18 years and older: 66-​143%

Female

1-​89 days: 15-​55%
90-​179 days: 35-​92%
180-​364 days: 45-​115%
1-​5 years: 62-​120%
6 years: 62-​130%
7-​9 years: 62-​151%
10-​11 years: 65-​142%
12-​13 years: 70-​140%
14-​15 years: 55-​145%
16-​17 years: 51-​147%
18 years and older: 57-​131%
Interpretive Data
Refer to report.
Note
CPT Code(s)
85303; 85306
Components
Component Test Code*Component Chart Name
0030113Protein C Functional
0030114Protein S Functional
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Protein C & S
  • Protein C and S Activity