Protein C and S Panel, Functional
0030182
Ordering Recommendation
Acceptable panel to detect protein C and S deficiencies.  Preferred test for detecting protein S deficiency is Protein S Free, Antigen (0098894). Do not order if the individual has been on warfarin therapy in the previous 2-4 weeks.
Mnemonic
C/S PANEL
Methodology
Clotting
Performed
Sun-Sat
Reported
1-2 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
CRITICAL FROZEN.  Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Serum. Non-frozen or hemolyzed specimens.  
Remarks
Include list of medications.  
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months  
Reference Interval
80-203%
 
Test Number Components Reference Interval
0030113Protein C, Functional 1-​4 days: 17-​53%
5-​29 days: 20-​64%
30-​89 days: 21-​65%
90-​179 days: 28-​80%
180-​364 days: 37-​81%
1-​6 years: 40-​92%
7-​9 years: 56-​144%
10-​11 years: 59-​143%
12-​13 years: 57-​142%
14-​15 years: 56-​162%
16-​17 years: 68-​154%
18 years and older: 77-​173%
0030114Protein S, Functional Male
1-​89 days: 15-​55%
90-​179 days: 35-​92%
180-​364 days: 45-​115%
1-​5 years: 62-​120%
6 years:  62-​130%
7-​9 years: 66-​140%
10-​11 years: 65-​139%
12-​13 years: 72-​139%
14-​15 years: 68-​145%
16-​17 years: 77-​167%
18 years and older: 66-​143%

Female

1-​89 days: 15-​55%
90-​179 days: 35-​92%
180-​364 days: 45-​115%
1-​5 years: 62-​120%
6 years:  62-​130%
7-​9 years: 62-​151%
10-​11 years: 65-​142%
12-​13 years: 70-​140%
14-​15 years: 55-​145%
16-​17 years: 51-​147%
18 years and older: 57-​131%
 
Interpretive Data
Refer to report.  
Note
 
CPT Code(s)
85303; 85306
Components
Component Test Code*Component Chart Name
0030113Protein C Functional
0030114Protein S Functional
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Protein C & S
  • Protein C and S Activity