Feedback
Protein C and S Panel, Total, Antigen
0030116
Ordering Recommendation
Not recommended. Preferred tests for detection of protein C and S deficiencies are Protein C Functional (0030113) and Protein S Free Antigen (0098894). Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
Mnemonic
C/S TOTAL
Methodology
Microlatex Particle-Mediated Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Serum. EDTA plasma, clotted or hemolyzed specimens.  
Remarks
 
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months  
Reference Interval
Test Number
Components
Reference Interval
0030111Protein C, Total Antigen1-4 days: 17-53%
5-29 days: 20-64%
30-89 days: 21-65%
90-179 days: 28-80%
180-364 days: 37-81%
1-5 years: 40-92%
6-10 years: 45-93%
11 years and older: 63-153%
0030112Protein S, Total Antigen
AgeMaleFemale
1-4 days12-60%12-60%
5-29 days22-78%22-78%
30-89 days33-93%33-93%
90-179 days54-118%54-118%
180-364 days55-119%55-119%
1-5 years54-118%54-118%
6-10 years41-114%41-114%
11 years and older84-134%63-126%



Interpretive Data
Refer to report.


Note
CPT Code(s)
85302; 85305
Components
Component Test Code*Component Chart NameLOINC
0030111Protein C, Total Antigen27820-0
0030112Protein S, Total Antigen27823-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Protein C & S, Antigen