Protein S, Total Antigen
0030112
 
Ordering Recommendation
Not recommended for detecting protein S deficiency; preferred test is Protein S Free, Antigen (0098894). Use to subtype deficiency in known protein S-deficient individuals in combination with Protein S Free, Antigen (0098894), or Protein S, Functional (0030114). Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
Mnemonic
PROT S
Methodology
Microlatex Particle-Mediated Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 1.5 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Serum. Non-frozen or hemolyzed specimens.  
Remarks
 
Stability
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months  
Reference Interval
1-4 days: 12-60%
5-29 days: 22-78%
30-89 days: 33-93%
90-179 days: 54-118%
180-364 days: 55-119%
1-5 years: 54-118%
6-10 years: 41-114%
11 years and older: Females: 63-126%; Males: 84-134%
Interpretive Data
Patients on warfarin may have decreased protein S values. Patients should be off warfarin therapy for two weeks for accurate measurement of protein S.
Note
CPT Code(s)
85305
Components
Component Test Code*Component Chart Name
0030112Protein S, Total Antigen
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Free Protein S Antigen
  • Protein S Antigen, S Protein Antigen
  • Total Protein S Antigen