ADAMTS13 Activity
0030056
Ordering Recommendation
 
Mnemonic
ADAMTS-13
Methodology
Chromogenic Assay
Performed
Mon-Sat
Reported
1-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 1 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Serum, EDTA plasma or hemolyzed specimens.  
Remarks
  
Stability
Ambient: 3 hours; Refrigerated: Unacceptable; Frozen: 2 weeks  
Reference Interval
Effective November 17, 2014

Greater than 60 percent  
Interpretive Data
ADAMTS13 levels of less than 5 percent may be associated with either inherited (Upshaw-Schulman Syndrome) or acquired thrombotic thrombocytopenic purpura (TTP).

A variety of medical conditions may result in a mild to moderate deficiency of ADAMTS13 activity. Recent plasma exchange therapy may raise the observed ADAMTS13 activity.

See Compliance Statement D: www.aruplab.com/CS
Statement D: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
 
CPT Code(s)
85397
Components
Component Test Code*Component Chart NameLOINC
0030049ADAMTS13 Activity53622-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • von Willebrand Factor Cleaving Protease