Carotenes, Fractionated, Plasma or Serum
Ordering Recommendation
Quantitative High Performance Liquid Chromatography
Mon, Wed, Fri
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Patient should fast overnight for 12 hours and should not consume alcohol for 24 hours prior to blood draw.  
Serum separator tube or green (sodium or lithium heparin).  
Specimen Preparation
Protect from light during collection, storage, and shipment. Separate serum or plasma from cells within 1 hour of collection. Transfer 1 mL serum or plasma to an ARUP Amber Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
Frozen. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
EDTA plasma, whole blood, or body fluids.  
After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 year  
Reference Interval
α-Carotene: 9-101 µg/L
β-Carotene: 42-373 µg/L
Lutein: 50-250 µg/L
Zeaxanthin: 8-80 µg/L  
Interpretive Data
Carotenoid concentrations may be decreased due to inadequate dietary fat consumption, intestinal parasitic infection or other malabsorption disorders; interactions from drugs such as cholestyramine, ethanol, weight-loss drugs, and fiber supplements; and kidney, liver, or pancreatic insufficiency. Carotenoid concentrations may be elevated due to hypothyroidism, hyperlipemia due to diabetes mellitus, myxedema, chronic nephritis, or vitamin supplementation.

See Compliance Statement B:
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
CPT Code(s)
Component Test Code*Component Chart NameLOINC
0021024Alpha Carotene56669-5
0021026Beta Carotene2053-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Alpha-Carotene
  • Beta-Carotene
  • Lutein
  • Provitamin A
  • Zeaxanthin