Alkaline Phosphatase Isoenzymes, Serum or Plasma
0021020
Ordering Recommendation
 
Mnemonic
ALKP-ISO
Methodology
Quantitative Heat Inactivation/Enzymatic
Performed
Sun-Sat
Reported
1-3 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube or green (sodium or lithium heparin).  
Specimen Preparation
Allow serum specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube and refrigerate or freeze immediately. (Min: 1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Specimens collected in EDTA, sodium fluoride, or potassium oxalate. Grossly hemolyzed or lipemic specimens.  
Remarks
  
Stability
After separation from cells: Ambient: 1 hour; Refrigerated: 1 week (total activity will increase 2 percent per day); Frozen: 1 year  
Reference Interval
 
 
Test Number Components   
0020005 Alkaline Phosphatase, Serum or Plasma Male
0-​30 days: 60-​320 U/L
1-​11 months: 70-​350 U/L
1-​3 years: 125-​320 U/L
4-​6 years: 150-​370 U/L
7-​9 years: 150-​440 U/L
10-​11 years: 150-​470 U/L
12-​13 years: 160-​500 U/L
14-​15 years: 130-​530 U/L
16-​19 years: 60-​270 U/L
20 years and older: 40-​120 U/L
Female
0-​30 days: 60-​320 U/L
1-​11 months: 70-​350 U/L
1-​3 years: 125-​320 U/L
4-​6 years: 150-​370 U/L
7-​9 years: 150-​440 U/L
10-​11 years: 150-​530 U/L
12-​13 years: 110-​525 U/L
14-​15 years: 55-​305 U/L
16-​19 years: 40-​120 U/L
20 years and older: 40-​120 U/L
 Bone Male
1-​6 years: 0-​208 U/L
7-​9 years: 0-​264 U/L
10-​15 years: 0-​340 U/L
16-​19 years: 0-​165 U/L
20 years and older: 0-​55 U/L
Female
1-​6 years: 0-​189 U/L
7-​9 years: 0-​246 U/L
10-​13 years: 0-​340 U/L
14-​15 years: 0-​91 U/L
16 years and older: 0-​55 U/L
 Liver Male
1-​6 years: 0-​145 U/L
7-​11 years: 0-​182 U/L
12-​15 years: 0-​226 U/L
16-​19 years: 0-​114 U/L
20 years and older: 0-​94 U/L
Female
1-​9 years: 0-​148 U/L
10-​15 years: 0-​162 U/L
16 years and older: 0-​94 U/L
Interpretive Data
Bone Specific Alkaline Phosphatase (0070053) and 5'Nucleotidase (0080235) may be useful in identifying disorders of bone and liver, respectively.  
Note
Heat-stable isoenzymes, such as the one produced during pregnancy, will interfere with the interpretation of this assay.
CPT Code(s)
84075; 84080
Components
Component Test Code*Component Chart Name
0020005Alkaline Phosphatase
0021006Alk-Phosphatase Other Calc
0021011Alk-Phosphatase Bone Calc
0021016Alk-Phosphatase Liver Calc
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ALK PHOS
  • Alkaline Phosphatase
  • Alkaline Phosphatase Isoenzymes by Heat Fractionation
  • Alkp