Thyroglobulin, Fine Needle Aspiration (FNA)
Ordering Recommendation

Use with FNA biopsy of thyroid nodules to diagnose benign or malignant non-medullary thyroid nodules.

Quantitative Chemiluminescent Immunoassay
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Fine needle aspiration in saline. 
Specimen Preparation
Centrifuge to remove cellular material. Specimen must be non-viscous and free of particulate matter. Transport 0.5 mL saline needle rinse. (Min: 0.5 mL) Also acceptable: Heparinized specimens. 
Storage/Transport Temperature
Unacceptable Conditions
Specimen types other than those listed. Specimens containing EDTA. Viscous specimens. 
Indicate source on test request form. 
Ambient: 8 hours; Refrigerated: 1 week; Frozen: 6 months 
Reference Interval
By report
Interpretive Data
Thyroglobulin (Tg) is measured by the Beckman Coulter Access method. Results obtained with different assay methods or kits cannot be used interchangeably. The Tg result, regardless of concentration, should not be interpreted as absolute evidence for the presence or absence of papillary or follicular thyroid cancer. This test is FDA cleared but is not labeled for use with FNA fluid.

The performance characteristics of this test were determined by ARUP.

Normal values are less than 10 ng/mL (Baloch ZW et al., CytoJournal 2008, 5:1).

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
Component Test Code*Component Chart NameLOINC
0020754Thyroglobulin, Fine Needle Aspiration53922-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • FNA TG