Zinc Protoporphyrin (ZPP), Whole Blood Industrial
0020614
 
Ordering Recommendation
Mnemonic
ZPP IND
Methodology
Quantitative Hematofluorometry
Performed
Mon-Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Lavender (EDTA), royal blue (EDTA), or tan (EDTA). Use royal blue (EDTA) tube when also testing for lead.  
Specimen Preparation
Transport 1 mL whole blood. (Min: 0.2 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Specimens not collected in EDTA. Clotted, frozen, or hemolyzed specimens.  
Remarks
 
Stability
Ambient: 30 hours; Refrigerated: 5 weeks; Frozen: Unacceptable  
Reference Interval
Test Number Components Reference Interval
Zinc Protoporphyrin (ZPP), Whole Blood 0-​40 µg/dL
Zinc Protoporphyrin (ZPP) to Heme Ratio 0-​69 µmol ZPP/mol heme
Interpretive Data
For occupational exposure to lead, OSHA requires ZPP whole blood concentration to be reported in units of µg/dL. For adults, conversion of ZPP to units of µg/dL assumes a hematocrit of 45%.
Note
Elevated ZPP results are seen in early and late iron deficiency, the anemia of chronic disease, chronic lead poisoning, and erythropoietic protoporphyria. Elevated bilirubin or riboflavin and hemolyzed, clotted, or improperly aliquoted specimens may falsely increase the ZPP concentration.
CPT Code(s)
84202
Components
Component Test Code*Component Chart Name
0020606Zinc Protoporphyrin - Ratio to Hgb
0020613Zinc Protoporphyrin, Blood
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • ZP
  • Porphyrins
  • ZPP
  • ZPP/Heme Ratio