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Creatine Kinase Isoenzymes
0020414
Ordering Recommendation

Aids in determining the etiology of elevated total creatine kinase. Cardiac troponins [troponin I (0090613) or troponin T (0098803)] are the recommended tests for diagnosis and management of acute coronary syndrome. May aid in identifying the presence of macro creatine kinase.

Mnemonic
CKISO
Methodology
Quantitative Enzymatic/Electrophoresis
Performed
Sun-Sat
Reported
Between 2 and 3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum separator tube or plain red. 
Specimen Preparation
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) 
Storage/Transport Temperature
Frozen. 
Unacceptable Conditions
Specimens preserved in citrate, EDTA, fluoride, heparin, or iodoacetate. Room temperature specimens. 
Remarks
This test will detect CK macroenzymes. 
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles) 
Reference Interval
Test Number
Components
Reference Interval
 CK-MM96-100%
 CK-MB0-4%
 CK-BB0%
 CK-Macro Type I0%
 CK-Macro Type II0%
 CK TotalEffective May 16, 2016
Age:
Male:
Female:
0-30 days
31 days-5 months
6-35 months
3-6 years
7-17 years
18 years and older:
108-564 U/L
72-367 U/L
50-272 U/L
56-281 U/L
60-393 U/L
20-200 U/L
108-564 U/L
72-367 U/L
38-261 U/L
40-222 U/L
46-250 U/L
20-180 U/L


Interpretive Data


Note
CPT Code(s)
82552; 82550
Components
Component Test Code*Component Chart NameLOINC
0020020CK-MM15049-0
0020021CK-MB12187-1
0020022CK-BB15048-2
0020108CK Total2157-6
2001881CK-Macro Type I26019-0
2001882CK-Macro Type II26020-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CK
  • CK Isoenzyme Electrophoresis
  • CK Isoenzymes
  • CK Macro
  • CK-BB
  • CK-MM
  • CKBB
  • CKMB
  • CPK
  • CPK Isoenzyme Electrophoresis
  • CPK Isoenzymes (Creatine Phosphokinase Isoenzymes)
  • Creatine Phosphokinase
  • Isoenzyme of Creatine Kinase
  • Isoenzymes, CK
  • Macro CK
  • Macro Creatine Kinase
  • Mitochondrial C